Dataset for: Cross-resistance to pesticides and pro-oxidants in Gulf killifish (Fundulus grandis) populations resistant to dioxin-like compounds (DLCs)

Relationship of Effects of Cardiac Outcomes in Fish for Validation of Ecological Risk (RECOVER)

DOI:
10.7266/N7513W6W
 
UDI:
R4.x258.258:0002
Last Update:
Jun 03 2016 19:06 UTC
 
Dataset Author(s):
Elias Oziolor, Benjamin Dubansky, Warren Burggren and Cole Matson
Point of Contact:
Munoz-Bustamante, Madeline
University of Miami / Rosenstiel School of Marine and Atmospheric Science
4600 Rickenbacker Cswy
Miami, Florida  33149
USA
mbustamante@rsmas.miami.edu
Funding Source:
RFP-IV
Data Collection Period:
2014-01-01 to 2016-03-01

Identified Submitted In-Review Available
3 3 3 3

Suggested Citation:

Elias Oziolor, Benjamin Dubansky, Warren Burggren and Cole Matson. 2016. Dataset for: Cross-resistance to pesticides and pro-oxidants in Gulf killifish (Fundulus grandis) populations resistant to dioxin-like compounds (DLCs). Distributed by: Gulf of Mexico Research Initiative Information and Data Cooperative (GRIIDC), Harte Research Institute, Texas A&M University–Corpus Christi. doi:10.7266/N7513W6W

Abstract:

This dataset is comprised of toxicity and biochemical and morphological assays that describe properties of resistance to dioxin-like compounds (DLCs) in four populations of Gulf killifish (Fundulus grandis) embryos. Two of these populations (Vince Bayou - VB and Paul's Bayou - PB) have been identified to be resistant to cardiac teratogenicity associated with exposure to polyaromatic hydrocarbons (PAHs.) Two reference populations were utilized for comparison (Gang's Bayou - GB and Smith Bayou -SP). Embyros were assessed for cross-resistance to pesticides (pyrethroid (permethrin), and carbamate (carbaryl)) and two model pro-oxidants (tert-butyl hydroquinone (tBHQ) and tert-butyl hydroperoxide (tBOOH)). Endpoints are mortality, degree of cardiac deformity, and the ethoxyresorufin-O-deethylase (EROD) assay to establish downregulation of cytochrome P450 1A as an indication of aryl-hydrocarbon receptor recalcitrance in resistant embryos. Morphological assays score the degree of heart deformities in embryos exposed to PCB-126.

Purpose:

The purpose was to determine if these populations are cross-resistant to both PAHs and oxidative stress, since there is much oxidative potential in the resistant populations (VB and PB.)

Theme Keywords:

pro-oxidant, oxidative stress, resistance, killifish, fundulus, EROD, toxicity, adaptation

File Format:

xml

Filename:

CrossResistanceToPesticidesPro-oxidants.xml (112.01 KB)

Dataset Downloads:

3

Dataset for: Cross-resistance to pesticides and pro-oxidants in Gulf killifish (Fundulus grandis) populations resistant to dioxin-like compounds (DLCs)



Identification Information
Distribution Information
Metadata Maintenance Information

Metadata: 
  File identifier: 
      R4.x258.258-0002-metadata.xml
  Language: 
      eng; USA
  Character set: 
    Character set code: 
      utf8
  Hierarchy level: 
    Scope code: 
      dataset
  Metadata author: 
    Responsible party: 
      Individual name: 
          Benjamin Dubansky
      Organisation name: 
          University of North Texas / Department of Biological Sciences
      Position name: 
      Contact info: 
        Contact: 
          Phone: 
            Telephone: 
              Voice: 
                  2259312937
              Facsimile: 
          Address: 
            Address: 
              Delivery point: 
                  1511 West Sycamore Street
                  Life Sciences Complex
              City: 
                  Denton
              Administrative area: 
                  TX
              Postal code: 
                  76203
              Country: 
                  USA
              Electronic mail address: 
                  benjamin.dubansky@unt.edu
      Role: 
        Role code: 
          pointOfContact
  Date stamp: 
      2021-05-04T20:04:57+00:00
  Metadata standard name: 
      ISO 19115-2 Geographic Information - Metadata - Part 2: Extensions for Imagery and Gridded Data
  Metadata standard version: 
      ISO 19115-2:2009(E)
  Dataset URI: 
      https://data.gulfresearchinitiative.org/metadata/R4.x258.258:0002
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Identification info: Data identification: Citation: Citation: Title: Dataset for: Cross-resistance to pesticides and pro-oxidants in Gulf killifish (Fundulus grandis) populations resistant to dioxin-like compounds (DLCs) Alternate title: Date: Date: Date: 2016-06-03 Date type: Date type code: publication Identifier: Identifier: Code: Anchor: xlink: https://dx.doi.org/10.7266/N7513W6W title: DOI doi:10.7266/N7513W6W Abstract: This dataset is comprised of toxicity and biochemical and morphological assays that describe properties of resistance to dioxin-like compounds (DLCs) in four populations of Gulf killifish (Fundulus grandis) embryos. Two of these populations (Vince Bayou - VB and Paul's Bayou - PB) have been identified to be resistant to cardiac teratogenicity associated with exposure to polyaromatic hydrocarbons (PAHs.) Two reference populations were utilized for comparison (Gang's Bayou - GB and Smith Bayou -SP). Embyros were assessed for cross-resistance to pesticides (pyrethroid (permethrin), and carbamate (carbaryl)) and two model pro-oxidants (tert-butyl hydroquinone (tBHQ) and tert-butyl hydroperoxide (tBOOH)). Endpoints are mortality, degree of cardiac deformity, and the ethoxyresorufin-O-deethylase (EROD) assay to establish downregulation of cytochrome P450 1A as an indication of aryl-hydrocarbon receptor recalcitrance in resistant embryos. Morphological assays score the degree of heart deformities in embryos exposed to PCB-126. Purpose: The purpose was to determine if these populations are cross-resistant to both PAHs and oxidative stress, since there is much oxidative potential in the resistant populations (VB and PB.) Status: Progress code: completed Point of contact: Responsible party: Individual name: Madeline Munoz-Bustamante Organisation name: University of Miami / Rosenstiel School of Marine and Atmospheric Science Position name: Program Manager Contact info: Contact: Phone: Telephone: Voice: Facsimile: Address: Address: Delivery point: 4600 Rickenbacker Cswy City: Miami Administrative area: Florida Postal code: 33149 Country: USA Electronic mail address: mbustamante@rsmas.miami.edu Role: Role code: pointOfContact Point of contact: Responsible party: Individual name: Benjamin Dubansky Organisation name: University of North Texas / Department of Biological Sciences Position name: Contact info: Contact: Phone: Telephone: Voice: 2259312937 Facsimile: Address: Address: Delivery point: 1511 West Sycamore Street Life Sciences Complex City: Denton Administrative area: TX Postal code: 76203 Country: USA Electronic mail address: benjamin.dubansky@unt.edu Role: Role code: pointOfContact Descriptive keywords: Keywords: Keyword: pro-oxidant Keyword: oxidative stress Keyword: resistance Keyword: killifish Keyword: fundulus Keyword: EROD Keyword: toxicity Keyword: adaptation Type: Keyword type code: theme Descriptive keywords: Keywords: Keyword: Texas Keyword: Galveston Type: Keyword type code: place Resource constraints: title: Cite As Constraints: Use limitation: Elias Oziolor, Benjamin Dubansky, Warren Burggren and Cole Matson. 2016. Dataset for: Cross-resistance to pesticides and pro-oxidants in Gulf killifish (Fundulus grandis) populations resistant to dioxin-like compounds (DLCs). Distributed by: Gulf of Mexico Research Initiative Information and Data Cooperative (GRIIDC), Harte Research Institute, Texas A&M University–Corpus Christi. doi:10.7266/N7513W6W Resource constraints: title: CC0 License Legal constraints: Use constraints: Restriction code: licenceUnrestricted Other constraints: This information is released under the Creative Commons license - No Rights Reserved - CC0 1.0 Universal (https://creativecommons.org/publicdomain/zero/1.0/). The person who associated a work with this deed has dedicated the work to the public domain by waiving all of his or her rights to the work worldwide under copyright law, including all related and neighboring rights, to the extent allowed by law. You can copy, modify, distribute and perform the work, even for commercial purposes, all without asking permission. Resource constraints: title: Liability and Warranty Legal constraints: Other constraints: All materials on this website are made available to GRIIDC and in turn to you "as-is." Content may only be submitted by an individual who represents and warrants that s/he has sufficient rights to be able to make the content available under a CC0 waiver. There is no warranty (expressed or implied) to these materials, their title, accuracy, non-infringement of third party rights, or fitness for any particular purpose, including the performance or results you may obtain from their use. Use these materials at your own risk. Under no circumstances shall GRIIDC be liable for any direct, incidental, special, consequential, indirect, or punitive damages that result from the use or the inability to use either this website or the materials available via this website. If you are dissatisfied with any website feature, content, or terms of use, your sole and exclusive remedy is to discontinue use. Aggregation Info: AggregateInformation: Aggregate Data Set Name: title: Related Publication Citation Citation: Title: Oziolor, E. M., Dubansky, B., Burggren, W. W., & Matson, C. W. (2016). Cross-resistance in Gulf killifish (Fundulus grandis) populations resistant to dioxin-like compounds. Aquatic Toxicology, 175, 222–231. doi:10.1016/j.aquatox.2016.03.019 Date: inapplicable Aggregate Data Set Identifier: title: Related Publication DOI Identifier: Code: Anchor: xlink: https://dx.doi.org/10.1016/j.aquatox.2016.03.019 title: DOI doi:10.1016/j.aquatox.2016.03.019 Association Type: Association type code: crossReference Language: eng; USA Topic category: Topic category code: biota Topic category: Topic category code: environment Extent: Extent: Geographic element: Geographic bounding box: West bound longitude: -95.22048 East bound longitude: -94.78559 South bound latitude: 29.25843 North bound latitude: 29.72823 Geographic element: BoundingPolygon: Polygon: gml:MultiPoint: gml:pointMember: Point: gml:pos: 29.54368 -94.78559 gml:pointMember: Point: gml:pos: 29.25843 -94.9125 gml:pointMember: Point: gml:pos: 29.71944 -95.22048 gml:pointMember: Point: gml:pos: 29.72823 -95.11403 Temporal element: Temporal extent: Extent: Time period: Description: ground condition Begin date: 2014-01-01 End date: 2016-03-01 Supplemental Information: Permethrin: Concentration (mass per unit volume); Mortality (percent mortality); Population (sampling population by site) tBHQ: tert-butyl hydroquinone (tBHQ) Concentration (mass per unit volume); Mortality (percent mortality); Population (sampling population by site) tBOOH: Model pro-oxidant tert-butyl hydroperoxide (tBOOH) Concentration (millimoles); Mortality (percent mortality); Population (sampling population by site) EROD: Dose (mL); EROD (fluorescence intensity of the urinary bladder, after background fluorescence was subtracted); Fluorescence intensity was box cox transformed for analysis. Population (sampling population by site) Cardiac Deformity: Dose (mL); Cardiac deformity index (scored quantitatively as 0=not deformed, 1=mildly deformed and 2=severely deformed); Population (sampling population by site); Rank Sampling site (abbreviation) latitude (decimal degrees) longitude (decimal degrees) Smith Point (SP) 29.543683 -94.785589 Gangs Bayou (GB) 29.258428 -94.9125 Vince Bayou (VB) 29.719444 -95.220481 Patrick Bayou (PB) 29.728233 -95.114031|Methods were performed as described in Oziolor et al. 2016 (http://dx.doi.org/10.1016/j.aquatox.2016.03.019)||||
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Distribution info: Distribution: Distributor: Distributor: Distributor contact: Responsible party: Organisation name: Gulf of Mexico Research Initiative Information and Data Cooperative (GRIIDC) Contact info: Contact: Phone: Telephone: Voice: 3618253604 Address: Address: Delivery point: 6300 Ocean Drive City: Corpus Christi Administrative area: TX Postal code: 78412 Country: USA Electronic mail address: griidc@gomri.org Online Resource: Online Resource: Linkage: URL: https://data.gulfresearchinitiative.org Role: Role code: distributor Distributor format: Format: Name: xml Version: inapplicable File decompression technique: Distributor transfer options: Digital transfer options: Transfer size: 0.112 Online: Online Resource: Linkage: URL: https://data.gulfresearchinitiative.org/data/R4.x258.258:0002 Protocol: https Name: Data Landing Page Description: GRIIDC dataset landing page Function: Online function code: information
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Metadata maintenance: Maintenance information: Maintenance and update frequency: unknown Maintenance note: This ISO metadata record was automatically generated from information provided to GRIIDC for dataset: R4.x258.258:0002 on 2021-10-20T12:23:31-05:00
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